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Employee Details

Prof. Rakesh Kumar Singh

Professor

Pharmacology and Toxicology,Regulatory Toxicology,

9810928555

rakesh[dot]singh[at]niperrbl[dot]ac[dot]in

 Areas of Interest

Translational studies on the molecular inflammatory pathways involved in chronic neurodegenerative diseases by both in-vitro and in-vivo approach.

15

Publications

7

Sponsored Projects

0

Doctoral Students

0

PG Dissertation

 Education Qualification

B.Pharm. (2004)
Dibrugarh University, Assam

India , Assam

M. Pharm. (2006)
National Institute of Pharmaceutical Education and Research (NIPER) - Mohali

India , Punjab

PHD (Award Date: 2017-12-13)
Role of MAPK Pathway in Chronic Inflammatory Diseases
Jamia Hamdard, New Delhi

India ,

 Experience

  •  Assistant Professor,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2020-02-20 - Present Working

  •  Associate Professor,  ,  Amity University,  Private,   2019-05-20 - 2020-02-17

  •  Assistant Professor,  ,  Apeejay Stya University,  Private,   2017-09-05 - 2019-05-15

  •  Senior Research Scientist,  ,  Daiichi Sankyo Research Centre in India,  Private,   2010-07-01 - 2017-01-31

  •  Research Scientist,  ,  Ranbaxy Research Laboratories,  Private,   2006-07-17 - 2010-06-30

  •  Chairman, Departmental Faculty Committee,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2023-01-17 - Present Working

  •  Chairman, Local Purchase Committee,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2022-04-01 - 2023-01-16

  •  Chairman, Departmental Academic Advisory Committee (DAAC),  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2021-10-21 - Present Working

  •  Chairman, Library committee,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2021-06-25 - 2022-12-30

  •  Chairman, Institutional Animal Ethics Committee (IAEC),  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2021-06-10 - Present Working

  •  Head of the Department of Pharmacology and Toxicology,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2021-03-12 - Present Working

  •  Chairperson of the Placement cell,  ,  National Institute of Pharmaceutical Education and Research Raebareli,  Central Government,   2020-07-01 - Present Working


  •  Publications

    0

    Google Scholar h-index

    0

    Google Scholar i10-index

    0

    Scopus h-index


    • IL-17 A Exacerbated Neuroinflammatory and Neurodegenerative Biomarkers in Intranasal Amyloid-Beta Model of Alzheimer’s Disease

      / Publisher Name: Springer / Journal Name: "Journal of Neuroimmune Pharmacology" / Volume Number: 20 / Publish Date Online: 2025-03-31 / Research Article / 2025 / Impact Factor: 5.2 / Accepted Web Link DOI

    • Intranasal amyloid model of Alzheimer’s disease - potential opportunities and challenges

      / Publisher Name: Springer / Journal Name: "Pharmacological Reports" / Volume Number: 77 / Publish Date Online: 2025-01-08 / Research Article / 2025 / Impact Factor: 3.6 / Accepted Web Link DOI

    • Therapeutic potential of chrysin in regulation of interleukin-17 signaling in a repeated intranasal amyloid-beta-induced Alzheimer's disease model

      / Publisher Name: Royal Society of Chemistry / Journal Name: "Food and Function" / Volume Number: 16 / Publish Date Online: 2024-12-17 / Research Article / 2024 / Impact Factor: 5.1 / Accepted Web Link DOI

    • IL-17A-Induced Redox Imbalance and Inflammatory Responses in Mice Lung via Act1-TRAF6-IKBα Signaling Pathway: Implications for Lung Disease Pathogenesis

      / Publisher Name: Springer / Journal Name: "Inflammation" / Publish Date Online: 2024-11-28 / Research Article / 2024 / Impact Factor: 4.5 / Accepted Web Link DOI

    • Identifying interventions that improve medication safety & rational use of medicines in India

      / Publisher Name: Medknow Publishers / Journal Name: "The Indian Journal of Medical Research" / Volume Number: 159 / Publish Date Online: 2024-08-03 / Research Article / 2024 / Impact Factor: 2.7 / Accepted Web Link DOI

    • Quercetin ameliorates neuroinflammatory and neurodegenerative biomarkers in the brain and improves neurobehavioral parameters in a repeated intranasal amyloid-beta exposed model of Alzheimer's disease

      / Publisher Name: Royal Society of Chemistry / Journal Name: "Food and Function" / Volume Number: 16 / Publish Date Online: 2024-07-19 / Research Article / 2024 / Impact Factor: 5.1 / Accepted Web Link DOI

    • MK2 inhibitor PF‐3644022 shows protective effect in mouse microglial N9 cell line induced with cigarette smoke extract

      / Publisher Name: Wiley / Journal Name: "Chemical Biology and Drug Design" / Volume Number: 104 / Publish Date Online: 2024-07-16 / Research Article / 2024 / Impact Factor: 3.2 / Accepted Web Link DOI

    • Toxicity Study of 3-Thienylalanine-Ornithine-Proline (TOP) Using as Novel ACE Inhibitor

      / Publisher Name: SPringer / Journal Name: "International Journal of Peptide Research and Therapeutics" / Volume Number: 28 / Publish Date Online: 2022-09-03 / Research Article / 2022 / Impact Factor: 2 / Accepted Web Link DOI

    • The clinical correlation of proinflammatory and anti-inflammatory biomarkers with Alzheimer disease: a meta-analysis

      / Publisher Name: Springer / Journal Name: "Neurological sciences" / Volume Number: 43 / Publish Date Online: 2022-05-25 / Research Article / 2022 / Impact Factor: 2.7 / Accepted Web Link DOI

    • Iron‐induced cellular in vitro neurotoxic responses in rat C6 cell line

      / Publisher Name: Wiley / Journal Name: "Environmental Toxicology" / Volume Number: 37 / Publish Date Online: 2022-04-21 / Research Article / 2022 / Impact Factor: 4.4 / Accepted Web Link DOI

    • Chronic oral exposure of aluminum chloride in rat modulates molecular and functional neurotoxic markers relevant to Alzheimer’s disease

      / Publisher Name: Taylor and Francis / Journal Name: "Toxicology Mechanisms and Methods" / Volume Number: 32 / Publish Date Online: 2022-04-07 / Research Article / 2022 / Impact Factor: 2.8 / Accepted Web Link DOI

    • The role of RIPK1 in chronic obstructive pulmonary disease

      / Publisher Name: Elsevier / Journal Name: "Drug Discovery Today" / Volume Number: 29 / Publish Date Online: 2024-05-18 / Review Article / 2024 / Impact Factor: 6.5 / Accepted Web Link DOI

    • Recent developments in nucleic acid-based therapies for Parkinson’s disease: current status, clinical potential, and future strategies

      / Publisher Name: Frontiers Publishers / Journal Name: "Frontiers in Pharmacology" / Volume Number: 13 / Publish Date Online: 2022-10-20 / Review Article / 2022 / Impact Factor: 4.4 / Accepted Web Link DOI

    • Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer’s disease

      / Publisher Name: Springer / Journal Name: "Pharmacological Reports" / Volume Number: 74 / Publish Date Online: 2022-01-27 / Review Article / 2022 / Impact Factor: 3.6 / Accepted Web Link DOI

    • Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

      / Publisher Name: Wiley / Journal Name: "Journal of Medical Virology" / Volume Number: 94 / Publish Date Online: 2021-10-21 / Review Article / 2021 / Impact Factor: 6.8 / Accepted Web Link DOI

    • Book Name: Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases (Chapter Title: The Link between gut microbiota and autoimmune dis) ,Publisher: Springer ,Level: International ,Total Pages: 33 , ISBN: 978-981-19-1946-6 /   Rakesh Kumar Singh, DOI

    • Book Name: Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases (Chapter Title: The Factors Influencing Gut Microbiota in Autoimmu) ,Publisher: Springer ,Level: International ,Total Pages: 69 , ISBN: 978-981-19-1946-6 /   Syed Afroz Ali, Samir Ranjan Panda, Mangaldeep Dey, Ashok Kumar Datusalia, V. G. M. Naidu, Rakesh Kumar Singh, DOI Web Link

    • Book Name: Drug Repurposing (Chapter Title: Implication of drug repurposing in the identificat) ,Publisher: De Gruyter ,Level: International ,Total Pages: 55 , ISBN: 9783110791143 /   Shikha Asthana, Vaibhav Lasure, Shivam Kumar Pandey, Avtar Singh Gautam, Rakesh Kumar Singh, DOI Web Link

    • Book Name: Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders (Chapter Title: Receptor Tyrosine Kinases in Neurodegenerative and) ,Publisher: Elsevier ,Level: International ,Total Pages: 45 , ISBN: 9780443186776 /   Chinna Babu Pulivarthi, Shruti Shikha Choubey, Shivam Kumar Pandey, Avtar Singh Gautam, Rakesh Kumar Singh, DOI Web Link

    • Book Name: Management of Migraine Pain: Emerging Opportunities and Challenges (Chapter Title: Currently Available Interventions for the Manageme) ,Publisher: Springer ,Level: International ,Total Pages: 191 , ISBN: 978-981-97-4529-6 /   Rakesh Kumar Singh, Shivam Kumar Pandey, Shreya Singh, Apoorva Chittoda, Sakshi Arun Chaudhari , DOI Web Link

    Synthesis and Evaluation of Nitrogen Tethered Derivatives in Cell-Based and Animal Models of Acute Lung Injury

    UPCST |  NIPER Raebareli |  1530000 |  25 Nov 2024 - 24 Nov 2027 | 

    Design, Synthesis, Characterization of Dibromo Indolizine analogs and Evaluation of their Anti-inflammatory Activity in vitro

    Uttar Pradesh COuncil of Science and Technology (UPCST), Lucknow, India, |  NIPER Raebareli |  900000 |  01 Mar 2024 - 28 Feb 2026 | 

    Dose-dependent effect of IL-17 induced lung inflammation in mice model

    National Institute of Pharmaceutical Education and Research, Raebareli |  NIPER Raebareli |  01 Aug 2023 - 28 Jun 2024 | 

    Effect of cigarette smoke extract on biomarkers of neuro-inflammation and oxidative stress in cell line.

    National Institute of Pharmaceutical Education and Research, Raebareli |  NIPER Raebareli |  01 Aug 2022 - 30 Jun 2023 | 

    Role of TLR4-p38MAPK-MK2 axis in amyloid beta-induced in-vitro and in-vivo model

    National Institute of Pharmaceutical Education and Research, Raebareli |  NIPER Raebareli |  01 Aug 2022 - 30 Jun 2023 | 

    Protective effect of NRF2 activator in allergens-induced lung inflammation.

    National Institute of Pharmaceutical Education and Research, Raebareli |  NIPER Raebareli |  01 Aug 2022 - 30 Jun 2023 | 

    Evaluation of RIPK1-induced Disease-associated Microglia response.

    National Institute of Pharmaceutical Education and Research, Raebareli |  NIPER Raebareli |  01 Aug 2022 - 30 Jun 2023 | 



      Training

    • Name: One day International Symposium on Drug Discovery and Development Interface,   Date(From - To): 2023-02-01 - 2023-02-01, Level: Organizing Secretary,  Designation: Internation within Country, No Of Participant: 450,

    • Name: 5-day certificate course on "Improving the Quality and Outcome of Experimental Research" conducted by NIPER-Raebareli,   Date(From - To): 2022-10-31 - 2022-11-05, Level: Member,  Designation: National,

    • Name: Lecture series on Regulatory Toxicology/Pharmacology by expert,   Date(From - To): 2022-07-01 - 2022-07-29, Level: Member,  Designation: National,

    • Events Name: International Conference on “Plants to Patients-Series III: Rethinking Ethnopharmacology", Location: National, Organizing Institute Name: Patanjali Research Foundation at Hardwar, Role: Keynote Speaker ,   Date(Start - End): 2023-02-28 - 2023-03-02,

    • Events Name: Faculty Development Program (FDP), Location: National, Organizing Institute Name: Dibrugarh University, Role: Expert Talk ,   Date(Start - End): 2022-07-29 - 2022-07-29,


     COURSES TAUGHT

    Department Course Name / Course Code Course Code

     Research Scholars

    Scholar Name Research Interest University Name Date of Registration Award Date Submitted Date Status

     Dissertations

    PG Dissertation

     Awards and Honours

    Awards and Honours

     Memberships / Fellowships

    • Lifetime Member- Society for alternatives to Animal Experimentation - India (SAAE - I), Member Reg. no: ,  Member Since: 2021,   Membership End: 0
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