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रा्ट्रीय औषधय शिक्षा और नुसंधान सं्थान
(रसायन और उर्वरक मंत्रालय, भारत रकार का औषध विभाग)
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH
(Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India)
(रसायन और उर्वरक मंत्रालय, भारत रकार का औषध विभाग)
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH
(Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India)
- +91-8810795920
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Employee Details
Rakesh Kumar Singh
Associate Professor
Medicinal Chemistry
9810928555
rakesh[dot]singh[at]niperrbl[dot]ac[dot]in
Areas of Interest
Translational studies on the molecular inflammatory pathways involved in chronic neurodegenerative diseases by both in-vitro and in-vivo approach.
45
Publications
18
Sponsored Projects
20
Doctoral Students
11
PG Dissertation
Education Qualification
B.Pharm. (2004)
Dibrugarh University, Assam
India , Assam
M. Pharm. (2006)
National Institute of Pharmaceutical Education and Research (NIPER) - Mohali
India , Punjab
PHD (Award Date: 2017-12-13)
Role of MAPK Pathway in Chronic Inflammatory Diseases
Jamia Hamdard, New Delhi
India ,
Experience
Publications
0
Google Scholar h-index
0
Google Scholar i10-index
0
Scopus h-index
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IL-17 A Exacerbated Neuroinflammatory and Neurodegenerative Biomarkers in Intranasal Amyloid-Beta Model of Alzheimer’s Disease
/ Publisher Name: Springer / Journal Name: "Journal of Neuroimmune Pharmacology" / Volume Number: 20 / Publish Date Online: 2025-03-31 / Research Article / 2025 / Impact Factor: 5.2 / Accepted Web Link DOI -
Intranasal amyloid model of Alzheimer’s disease - potential opportunities and challenges
/ Publisher Name: Springer / Journal Name: "Pharmacological Reports" / Volume Number: 77 / Publish Date Online: 2025-01-08 / Research Article / 2025 / Impact Factor: 3.6 / Accepted Web Link DOI -
Therapeutic potential of chrysin in regulation of interleukin-17 signaling in a repeated intranasal amyloid-beta-induced Alzheimer's disease model
/ Publisher Name: Royal Society of Chemistry / Journal Name: "Food and Function" / Volume Number: 16 / Publish Date Online: 2024-12-17 / Research Article / 2024 / Impact Factor: 5.1 / Accepted Web Link DOI -
IL-17A-Induced Redox Imbalance and Inflammatory Responses in Mice Lung via Act1-TRAF6-IKBα Signaling Pathway: Implications for Lung Disease Pathogenesis
/ Publisher Name: Springer / Journal Name: "Inflammation" / Publish Date Online: 2024-11-28 / Research Article / 2024 / Impact Factor: 4.5 / Accepted Web Link DOI -
Identifying interventions that improve medication safety & rational use of medicines in India
/ Publisher Name: Medknow Publishers / Journal Name: "The Indian Journal of Medical Research" / Volume Number: 159 / Publish Date Online: 2024-08-03 / Research Article / 2024 / Impact Factor: 2.7 / Accepted Web Link DOI -
Quercetin ameliorates neuroinflammatory and neurodegenerative biomarkers in the brain and improves neurobehavioral parameters in a repeated intranasal amyloid-beta exposed model of Alzheimer's disease
/ Publisher Name: Royal Society of Chemistry / Journal Name: "Food and Function" / Volume Number: 16 / Publish Date Online: 2024-07-19 / Research Article / 2024 / Impact Factor: 5.1 / Accepted Web Link DOI -
MK2 inhibitor PF‐3644022 shows protective effect in mouse microglial N9 cell line induced with cigarette smoke extract
/ Publisher Name: Wiley / Journal Name: "Chemical Biology and Drug Design" / Volume Number: 104 / Publish Date Online: 2024-07-16 / Research Article / 2024 / Impact Factor: 3.2 / Accepted Web Link DOI -
Toxicity Study of 3-Thienylalanine-Ornithine-Proline (TOP) Using as Novel ACE Inhibitor
/ Publisher Name: SPringer / Journal Name: "International Journal of Peptide Research and Therapeutics" / Volume Number: 28 / Publish Date Online: 2022-09-03 / Research Article / 2022 / Impact Factor: 2 / Accepted Web Link DOI -
The clinical correlation of proinflammatory and anti-inflammatory biomarkers with Alzheimer disease: a meta-analysis
/ Publisher Name: Springer / Journal Name: "Neurological sciences" / Volume Number: 43 / Publish Date Online: 2022-05-25 / Research Article / 2022 / Impact Factor: 2.7 / Accepted Web Link DOI -
Iron‐induced cellular in vitro neurotoxic responses in rat C6 cell line
/ Publisher Name: Wiley / Journal Name: "Environmental Toxicology" / Volume Number: 37 / Publish Date Online: 2022-04-21 / Research Article / 2022 / Impact Factor: 4.4 / Accepted Web Link DOI -
Chronic oral exposure of aluminum chloride in rat modulates molecular and functional neurotoxic markers relevant to Alzheimer’s disease
/ Publisher Name: Taylor and Francis / Journal Name: "Toxicology Mechanisms and Methods" / Volume Number: 32 / Publish Date Online: 2022-04-07 / Research Article / 2022 / Impact Factor: 2.8 / Accepted Web Link DOI
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The role of RIPK1 in chronic obstructive pulmonary disease
/ Publisher Name: Elsevier / Journal Name: "Drug Discovery Today" / Volume Number: 29 / Publish Date Online: 2024-05-18 / Review Article / 2024 / Impact Factor: 6.5 / Accepted Web Link DOI -
Recent developments in nucleic acid-based therapies for Parkinson’s disease: current status, clinical potential, and future strategies
/ Publisher Name: Frontiers Publishers / Journal Name: "Frontiers in Pharmacology" / Volume Number: 13 / Publish Date Online: 2022-10-20 / Review Article / 2022 / Impact Factor: 4.4 / Accepted Web Link DOI -
Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer’s disease
/ Publisher Name: Springer / Journal Name: "Pharmacological Reports" / Volume Number: 74 / Publish Date Online: 2022-01-27 / Review Article / 2022 / Impact Factor: 3.6 / Accepted Web Link DOI -
Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19
/ Publisher Name: Wiley / Journal Name: "Journal of Medical Virology" / Volume Number: 94 / Publish Date Online: 2021-10-21 / Review Article / 2021 / Impact Factor: 6.8 / Accepted Web Link DOI
- Book Name: Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases (Chapter Title: The Link between gut microbiota and autoimmune dis) ,Publisher: Springer ,Level: International ,Total Pages: 33 , ISBN: 978-981-19-1946-6 / Rakesh Kumar Singh, DOI
- Book Name: Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases (Chapter Title: The Factors Influencing Gut Microbiota in Autoimmu) ,Publisher: Springer ,Level: International ,Total Pages: 69 , ISBN: 978-981-19-1946-6 / Syed Afroz Ali, Samir Ranjan Panda, Mangaldeep Dey, Ashok Kumar Datusalia, V. G. M. Naidu, Rakesh Kumar Singh, DOI Web Link
- Book Name: Drug Repurposing (Chapter Title: Implication of drug repurposing in the identificat) ,Publisher: De Gruyter ,Level: International ,Total Pages: 55 , ISBN: 9783110791143 / Shikha Asthana, Vaibhav Lasure, Shivam Kumar Pandey, Avtar Singh Gautam, Rakesh Kumar Singh, DOI Web Link
- Book Name: Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders (Chapter Title: Receptor Tyrosine Kinases in Neurodegenerative and) ,Publisher: Elsevier ,Level: International ,Total Pages: 45 , ISBN: 9780443186776 / Chinna Babu Pulivarthi, Shruti Shikha Choubey, Shivam Kumar Pandey, Avtar Singh Gautam, Rakesh Kumar Singh, DOI Web Link
- Book Name: Management of Migraine Pain: Emerging Opportunities and Challenges (Chapter Title: Currently Available Interventions for the Manageme) ,Publisher: Springer ,Level: International ,Total Pages: 191 , ISBN: 978-981-97-4529-6 / Rakesh Kumar Singh, Shivam Kumar Pandey, Shreya Singh, Apoorva Chittoda, Sakshi Arun Chaudhari , DOI Web Link
Synthesis and Evaluation of Nitrogen Tethered Derivatives in Cell-Based and Animal Models of Acute Lung Injury
UPCST | NIPER Raebareli | 1530000 | 25 Nov 2024 - 24 Nov 2027 |
Design, Synthesis, Characterization of Dibromo Indolizine analogs and Evaluation of their Anti-inflammatory Activity in vitro
Uttar Pradesh COuncil of Science and Technology (UPCST), Lucknow, India, | NIPER Raebareli | 900000 | 01 Mar 2024 - 28 Feb 2026 |
Dose-dependent effect of IL-17 induced lung inflammation in mice model
National Institute of Pharmaceutical Education and Research, Raebareli | NIPER Raebareli | 01 Aug 2023 - 28 Jun 2024 |
Effect of cigarette smoke extract on biomarkers of neuro-inflammation and oxidative stress in cell line.
National Institute of Pharmaceutical Education and Research, Raebareli | NIPER Raebareli | 01 Aug 2022 - 30 Jun 2023 |
Role of TLR4-p38MAPK-MK2 axis in amyloid beta-induced in-vitro and in-vivo model
National Institute of Pharmaceutical Education and Research, Raebareli | NIPER Raebareli | 01 Aug 2022 - 30 Jun 2023 |
Protective effect of NRF2 activator in allergens-induced lung inflammation.
National Institute of Pharmaceutical Education and Research, Raebareli | NIPER Raebareli | 01 Aug 2022 - 30 Jun 2023 |
Evaluation of RIPK1-induced Disease-associated Microglia response.
National Institute of Pharmaceutical Education and Research, Raebareli | NIPER Raebareli | 01 Aug 2022 - 30 Jun 2023 |
Employee Seed Money / Colaboration / MoUs
Training
- Name: One day International Symposium on Drug Discovery and Development Interface, Date(From - To): 2023-02-01 - 2023-02-01, Level: Organizing Secretary, Designation: Internation within Country, No Of Participant: 450,
- Name: 5-day certificate course on "Improving the Quality and Outcome of Experimental Research" conducted by NIPER-Raebareli, Date(From - To): 2022-10-31 - 2022-11-05, Level: Member, Designation: National,
- Name: Lecture series on Regulatory Toxicology/Pharmacology by expert, Date(From - To): 2022-07-01 - 2022-07-29, Level: Member, Designation: National,
- Events Name: International Conference on “Plants to Patients-Series III: Rethinking Ethnopharmacology", Location: National, Organizing Institute Name: Patanjali Research Foundation at Hardwar, Role: Keynote Speaker , Date(Start - End): 2023-02-28 - 2023-03-02,
- Events Name: Faculty Development Program (FDP), Location: National, Organizing Institute Name: Dibrugarh University, Role: Expert Talk , Date(Start - End): 2022-07-29 - 2022-07-29,
Research Scholars
| Scholar Name | Research Interest | University Name | Date of Registration | Award Date | Submitted Date | Status |
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