Projects

Exploration of oxadiazole scaffolds into
potential pan peroxisome proliferator-activated
receptors (PPARs) agonists as antidiabetic
agents

Design, Synthesis, Characterization of Dibromo
Indolizine analogs and Evaluation of their
Anti-inflammatory Activity in vitro

Synthesis and Evaluation of Nitrogen Tethered
Derivatives in Cell-Based and Animal Models of
Acute Lung Injury

Synthesis and evaluation of novel dual
GSK-3β/HDAC inhibitor as an anti-Alzheimer
agent.

To investigate

Dose-dependent effect of IL-17 induced lung
inflammation in mice model

Development of modified kynurenic acid-based
scaffolds for treatment of post-traumatic stress
disorder

Designing of senolytic agents for the treatment
of Alzheimers disease

Effect of cigarette smoke extract on biomarkers
of neuro-inflammation and oxidative stress in cell
line.

Role of TLR4-p38MAPK-MK2 axis in amyloid
beta-induced in-vitro and in-vivo model

Protective effect of NRF2 activator in
allergens-induced lung inflammation.

Evaluation of RIPK1-induced Disease-associated
Microglia response.

Discovering the anti-inflammatory effects of
novel Toll-like receptor signaling inhibitors on
rheumatoid arthritis mononuclear cells and
synovial fibroblasts- An in vitro study to
identify TLR signaling inhibition in rheumatoid
arthritis

Novel synthesis of flavonoid-hydroxypyridinone
hybrids as potential anti-Alzheimer agents.

Exploring the immunomodulatory activities of
novel Toll-like receptor-signaling inhibitors in
peripheral blood mononuclear cells from lupus
patients: A study to identify TLRs as drug targets
for lupus